AEBP2

Formats

Anti-AEBP2 Recombinant Antibody Products

Mouse Anti-AEBP2 Recombinant Antibody (clone 3023D5b) (MOB-0531MZ)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB
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Mouse Anti-AEBP2 Recombinant Antibody (clone 3E3C10) (VS7-HM48)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ICC
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For Research Use Only. Not For Clinical Use.

Protein class

Transcription factors

Predicted location

Intracellular

Single cell type specificity

Low cell type specificity

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Self-associates (PubMed:15225548). Associates with the PRC2 complex, which consists of the core components EED, EZH1 or EZH2, SUZ12, and RBBP4, and various combinations of accessory subunits including AEBP2, JARID2, PHF19, MTF2 and EPOP (PubMed:12351676, PubMed:15225548, PubMed:31959557, PubMed:29499137). Found in a monomeric PRC2.2 (class 2) complex consisting of at least SUZ12, RBBP4, AEBP2 and JARID2 (PubMed:29499137). Within the PRC2 complex, interacts directly with SUZ12; competes with PHF19 for SUZ12 binding (PubMed:12351676, PubMed:29499137). Interacts with EED, EZH2, and RBBP4 (PubMed:12351676, PubMed:15225548). May also interact with RBBP7 (PubMed:12351676).

Molecular function

Chromatin regulator, DNA-binding, Repressor

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