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AGPAT2
Loading...Anti-AGPAT2 Products
- Recombinant Anti-Human AGPAT2 Antibody Fab Fragment (MOB-3910z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: RIA, ELISA, FuncS
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- Recombinant Anti-Human AGPAT2 Antibody scFv Fragment (MOB-3910z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: Neut, WB, FuncS
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For Research Use Only. Not For Clinical Use.
This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Proximal enterocytes, Distal enterocytes, Paneth cells, Late spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HDLM-2)
Molecular function
Acyltransferase, Transferase
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