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AIFM2

Anti-AIFM2 Products

Mouse Anti-AIFM2 Recombinant Antibody (clone HR231) (ZG-0843F)
- Species Reactivity: Human, Monkey, Mouse, Rat
- Type: Mouse IgG2b
- Application: ELISA, WB, IP, IHC
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Mouse Anti-AIFM2 Recombinant Antibody (clone Pab122) (ZG-0884F)
- Species Reactivity: Human, Mouse, Rat, Monkey, Hamster
- Type: Mouse IgG2b
- Application: IP, FC, IF
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Mouse Anti-AIFM2 Recombinant Antibody (clone CBLS-096) (MOB-0610MZ)
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: ELISA
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Anti-Mouse AIFM2 Immunohistochemistry Kit (VS-0525-XY246)
- Species Reactivity: Human, Mouse, Rat, Hamster
- Target: AIFM2
- Application: IHC
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Anti-AIFM2 Immunohistochemistry Kit (VS-0325-XY68)
- Species Reactivity: Human, Mouse, Rat
- Target: AIFM2
- Application: IHC
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For Research Use Only. Not For Clinical Use.

This gene encodes a flavoprotein oxidoreductase that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of this gene is also found to be induced by tumor suppressor protein p53 in colon cancer cells. [provided by RefSeq, Nov 2010]

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Distal enterocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (Hep G2)

Interaction

Interacts with importin subunits KPNA2 and IPO5; this interaction likely mediates the translocation into the nucleus upon oxidative stress.

Molecular function

DNA-binding, Oxidoreductase

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