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AK5

This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Oligodendrocytes, Excitatory neurons, Inhibitory neurons, Early spermatids)

Immune cell specificity

Immune cell enhanced (naive CD4 T-cell, myeloid DC)

Cell line specificity

Cell line enhanced (ASC TERT1, BJ, fHDF/TERT166, LHCN-M2, U-2 OS)

Interaction

Monomer. Interacts with YWHAZ (PubMed:16959763).

Molecular function

Kinase, Transferase

More Types Infomation

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For Research Use Only. Not For Clinical Use.

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