Loading...
ALAS2
The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
Protein class
Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Erythroid cells)
Immune cell specificity
Immune cell enriched (plasmacytoid DC)
Cell line specificity
Group enriched (HEL, K-562)
Interaction
Homodimer (PubMed:32499479). Interacts with SUCLA2 (PubMed:14643893, PubMed:32499479). [Isoform 4]: Interacts with SUCLA2.
Molecular function
Acyltransferase, Transferase
More Types Infomation
-
- Species Reactivity: Human
- Type: Mouse IgG2a
- Application: ELISA, WB
-
- Derivation: Phage display library screening
- Species Reactivity: Mouse, Rat, Human
- Type: Rabbit IgG
- Application: WB, FC, IP
-
- Derivation: Mouse
- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG1
- Application: WB, IP, IF, IHC
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IP
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
For Research Use Only. Not For Clinical Use.