AMBRA1
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Loading...- Anti-AMBRA1 Immunohistochemistry Kit (VS-0325-XY105)
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- Species Reactivity: Human, Mouse
- Target: AMBRA1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Enables enzyme binding activity; protein phosphatase activator activity; and ubiquitin-like ligase-substrate adaptor activity. Involved in several processes, including macroautophagy; positive regulation of free ubiquitin chain polymerization; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Located in cytosol. Part of Cul4-RING E3 ubiquitin ligase complex. Is active in cytoskeleton; mitochondrion; and nucleus. Biomarker of multiple system atrophy.