Anti-AMPD1 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs provides your research with a diverse selection of high-quality anti-AMPD1 antibodies. Targeting AMPD1 is essential for advancing understanding and developing potential therapies for various myopathies and cardiovascular diseases. Our high-quality and rigorously validated antibody products enable the precision, reliability, and speed your studies of this exciting therapeutic target need to help you advance.

AMPD1: A Pivotal Target for Cardiac Disease & Muscle Metabolism

AMPD1 (adenosine monophosphate deaminase 1), also known as AMP deaminase 1, is an enzyme that primarily exists in skeletal muscle and plays a pivotal role in cellular energy metabolism by catalyzing the deamination of AMP to IMP, as part of the purine nucleotide cycle. Deficiency of AMPD1 is the most common metabolic myopathy in humans and is associated with muscle pain and fatigue following exercise. Intriguingly, genetic variants of the enzyme are paradoxically linked with reduced rates of heart failure, making this enzyme an attractive and necessary therapeutic target for further study.

Alternative Names

HAVCR; HAVCR-1; KIM-1; KIM1; TIM; TIM-1; TIM1; TIMD-1; TIMD1; CD365; hepatitis A virus cellular receptor 1; HAVcr-1; T-cell immunoglobulin and mucin domain 1.

Background

Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Anti-AMPD1 rAb Products

Our recombinant anti-AMPD1 antibodies are engineered for exceptional performance. Possessing high specificity and affinity, they minimize off-target effects and deliver clean, reliable data. Trust our antibodies to provide the credible, reproducible results necessary to confidently advance your research into AMPD1's role in metabolic and cardiovascular diseases.

Table 1. Featured anti-AMPD1 recombinant antibody products at Creative Biolabs.

Creative Quality Control

Our anti-AMPD1 antibodies are made using the most optimized manufacturing pipelines to produce the most reliable products. These antibodies are subject to a stringent quality control (QC) process, which includes full validation using Western Blot, and IP where applicable. This process results in products that show superior performance, specificity, and lot-to-lot consistency so you can trust our products to give you reproducible, impactful results while saving you time and money.

Customer Reviews

rAb Production

Creative Biolabs uses the latest recombinant antibody technology to make our anti-AMPD1 products. We make use of both prokaryotic (e.g., E. coli) and the most advanced eukaryotic (e.g., HEK293, CHO) expression systems. We can use any system that results in the optimal product for your purposes by allowing for proper antibody folding, and, where necessary, post-translational modifications to produce high-purity, high-activity antibodies with minimal batch-to-batch variability for your most demanding applications.

Featured Anti-AMPD1 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-AMPD1 recombinant antibody production.

Fig.2 Gram-scale anti-AMPD1 recombinant antibody production.

rAb Modalities

Creative Biolabs offers high-quality, customizable recombinant antibodies for your research targeting AMPD1. Our anti-AMPD1 recombinant antibodies are available in a variety of formats, such as full-length IgG, Fab, and scFv fragments, and can be fully customized to suit the unique needs of the local, national, and international research community.

Fig.3 Full-length anti-AMPD1 recombinant antibody production and modalities.

Creative Biolabs is your trusted partner for accelerating research into conditions related to AMPD1. Our high-quality anti-AMPD1 recombinant antibodies offer the precision you need to study this important enzyme's complex role in myopathies, cardiovascular disease, and even oncology. Give your studies the boost they need with our validated antibody products today. Reach out to our team of experts to learn more about our products and how we can help you achieve your research goals.