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ANGPT1

Anti-ANGPT1 Products
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB
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- Derivation: Rabbit
- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB, IHC
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ELISA
- Recombinant Anti-Human ANGPT1 VHH Single Domain Antibody (NAB-178-VHH)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, ICC, ChiP, FA, ELISA
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- Derivation: Phage display library screening
- Species Reactivity: Rat, Human
- Type: Rabbit IgG
- Application: WB
- Anti-ANGPT1 Immunohistochemistry Kit (VS-0525-XY364)
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- Species Reactivity: Human
- Target: ANGPT1
- Application: IHC
- Anti-Mouse ANGPT1 Immunohistochemistry Kit (VS-0525-XY365)
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- Species Reactivity: Human, Mouse, Rat
- Target: ANGPT1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.