Disease related genes, Human disease related genes
Intracellular, Membrane (different isoforms)
Cell type enhanced (Spermatocytes, Urothelial cells)
Low immune cell specificity
Low cell line specificity
Interacts with BAF/BANF1. Interacts with protein phosphatase 2A (PP2A) components PPP2C (PPP2CA or PPP2CB) and PPP2R1A. (Microbial infection) May interact with non-structural protein 4A/NS4A from Zika virus strains Mr-766 or French Polynesia 10087PF/2013; the interaction may inhibit ANKLE2 function and contribute to defects in brain development, such as microcephaly.
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For Research Use Only. Not For Clinical Use.