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ANKRD13A
Anti-ANKRD13A Recombinant Antibody Products
- Recombinant Anti-Human ANKRD13A Antibody (MOB-2891z)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, IF, FuncS
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- Recombinant Anti-Human ANKRD13A Antibody Fab Fragment (MOB-2891z-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: WB, Neut, FuncS
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- Recombinant Anti-Human ANKRD13A Antibody scFv Fragment (MOB-2891z-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: ELISA, WB, FuncS
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For Research Use Only. Not For Clinical Use.
Ubiquitin-binding protein that specifically recognizes and binds Lys-63-linked ubiquitin. Does not bind Lys-48-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Late spermatids)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (fHDF/TERT166, HBF TERT88)
Interaction
Interacts (via the UIM 3 and 4 repeats) with EGFR (ubiquitinated); the interaction is direct, inhibited by ANKRD13A monoubiquitination and may regulate EGFR internalization.
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