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ANP32A
Loading...Anti-ANP32A Products
- Recombinant Mouse Anti-Human ANP32A Antibody (MOB-1267MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: ICC/IF, IHC-P, WB
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- AbPlus™ Anti-ANP32A Magnetic Beads (VS-0724-YC1026) (VS-0724-YC1026)
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- Target: ANP32A
- Target Species: Human
- Application: IP, Protein Purification
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- Anti-ANP32A Immunohistochemistry Kit (VS-0325-XY113)
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- Species Reactivity: Human, Mouse, Rat
- Target: ANP32A
- Application: IHC
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- Mouse Anti-ANP32A Monoclonal Antibody (clone 8D2) (VS7-0425-WR653)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC
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For Research Use Only. Not For Clinical Use.
Background
Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the SET complex, composed of at least ANP32A, APEX1, HMGB2, NME1, SET and TREX1. Directly interacts with SET. Interacts with ATXN1/SCA1. Interacts with MAP1B. Interacts with ELAVL1. Part of the INHAT (inhibitor of histone acetyltransferases) complex. Interacts with E4F1. (Microbial infection) Interacts (via C-terminus) with influenza virus A protein PB2; this interaction promotes viral replication. (Microbial infection) Interacts (via C-terminus) with influenza virus B protein PB2; this interaction promotes viral replication. (Microbial infection) Interacts (via C-terminus) with influenza virus C protein PB2; this interaction promotes viral replication by bridging viral replicase dimers together.
Molecular function
Repressor
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