Anti-ANXA3 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs offers a comprehensive catalog of state-of-the-art anti-Annexin A3 (ANXA3) recombinant antibodies, including IgGs and engineered formats, to support your research in cancer, inflammation, and differentiation. ANXA3 is a rapidly emerging biomarker and functional player in chemoresistance and tumor progression. Our validated, highly specific, and reliable antibodies will empower you to discover the therapeutic potential of targeting this protein in disease settings.

ANXA3: An Emerging Factor in Chemoresistance and Cancer

ANXA3 is a calcium-dependent phospholipid-binding protein belonging to the annexin superfamily. Involved in various cellular processes, such as vesicle trafficking, membrane repair, and the regulation of phospholipase A2 activity. In disease, ANXA3 has garnered significant interest in cancer research. High expression of ANXA3 is linked to poor prognosis and chemoresistance in various cancers, including ovarian, prostate, and liver cancer. ANXA3 is thought to confer drug resistance by modulating cellular stress responses and drug efflux, making it a promising target for overcoming treatment resistance.

Alternative Names

Annexin A3; Inositol 1,2-Cyclic Phosphate 2-Phosphohydrolase; Placental Anticoagulant Protein III; 35-Alpha Calcimedin; Lipocortin III; Annexin-3; PAP-III;

Background

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation. [provided by RefSeq, Jul 2008]

Protein class

FDA approved drug targets, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Pancreatic endocrine cells, Alveolar cells type 1, Ductal cells, Adipocytes, Exocrine glandular cells)

Immune cell specificity

Immune cell enriched (neutrophil)

Cell line specificity

Cell line enhanced (A-431, CACO-2, CAPAN-2, EFO-21, hTERT-HME1, OE19, RPTEC TERT1)

Molecular function

Phospholipase A2 inhibitor

More Types Infomation

Anti-ANXA3 rAb Products

Our anti-ANXA3 recombinant antibodies are carefully designed and produced to the highest standards of scientific excellence. These rAbs are rigorously validated for specificity to ensure precise detection of ANXA3 without cross-reactivity with other annexins. They demonstrate high affinity and robust performance in multiple validated applications, providing the confidence and clarity needed to explore ANXA3's function in your model system.

Table 1. Featured anti-ANXA3 recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
VS-0923-FY15 Recombinant Mouse Anti-ANXA3 Antibody (VS-0923-FY15) (CAT#: VS-0923-FY15) Human Mouse IgG2b ELISA, WB
MOB-0621MZ Mouse Anti-ANXA3 Recombinant Antibody (clone CBLS-098) (CAT#: MOB-0621MZ) Human Mouse IgG1 WB

Customer Reviews

Excellent
Ma**y
Recombinant Mouse Anti-ANXA3 Antibody (VS-0923-FY15) (CAT#: VS-0923-FY15)
We used this recombinant antibody for proteomic analysis of extracellular vesicles. It worked beautifully, giving us strong and specific signal for ANXA3, which was crucial for the success of our project.
07/Aug/2024

rAb Production

Creative Biolabs has the expertise and the state-of-the-art technologies necessary to support your research with a wide variety of production methods. Our production capabilities include the ability to express anti-ANXA3 recombinant antibodies in simple prokaryotic systems as well as in eukaryotic systems, including CHO and HEK293 cell lines. This allows us to produce recombinant antibodies with the desired structural integrity and post-translational modifications for optimal performance across a wide range of assays.

Featured Anti-ANXA3 Recombinant Antibody Production PlatformsMilligram-scale. (Creative Biolabs Original)
Fig.1 Milligram-scale anti-ANXA3 recombinant antibody production.

Gram-scale. (Creative Biolabs Original)Fig.2 Gram-scale anti-ANXA3 recombinant antibody production.

rAb Modalities

Creative Biolabs is committed to pushing the boundaries of science by offering flexible and innovative antibody modalities. Our anti-ANXA3 recombinant antibodies can be produced in a variety of formats from full-length IgGs for functional studies, to smaller, engineered fragments like scFvs and Fabs for specific diagnostic or therapeutic applications, tailored to meet the needs of researchers all over the world.

ANXA3 antibody production and modalities. (Creative Biolabs Original)Fig.3 Full-length anti-ANXA3 recombinant antibody production and modalities.

Empower your research into the role of Annexin A3 in disease with Creative Biolabs' premium recombinant antibodies. We take pride in providing only the highest quality products that are defined by high specificity, comprehensive validation, and consistent performance, giving you the confidence and tools you need to make important discoveries with this exciting therapeutic target. Don't wait to build your research on a foundation of quality. Contact one of our experts today.

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