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ANXA8
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes a member of the annexin family of evolutionarily conserved Ca2+ and phospholipid binding proteins. The encoded protein may function as an an anticoagulant that indirectly inhibits the thromboplastin-specific complex. Overexpression of this gene has been associated with acute myelocytic leukemia. A highly similar duplicated copy of this gene is found in close proximity on the long arm of chromosome 10.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Alveolar cells type 1, Squamous epithelial cells, Oligodendrocyte precursor cells, Oligodendrocytes, Excitatory neurons, Inhibitory neurons, Club cells, Astrocytes, Microglial cells, Fibroblasts)
Immune cell specificity
Immune cell enhanced (myeloid DC)
Cell line specificity
Cell line enhanced (HaCaT, HBEC3-KT, hTCEpi, hTERT-HME1, RT4)
More Types Infomation