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AP3B2

Anti-AP3B2 Products

Chicken Anti-AP3B2 Polyclonal IgY (BRD-0897MZ)
- Species Reactivity: Human
- Type: Chicken antibody
- Application: ICC, IF
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For Research Use Only. Not For Clinical Use.

Background

Adaptor protein-3 (AP3) is a heterotetrameric vesicle-coat protein complex. Some AP3 subunits are ubiquitously expressed, whereas others are expressed exclusively in neurons. The neuron-specific AP3 complex, which includes AP3B2, is thought to serve neuron-specific functions such as neurotransmitter release.

Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Excitatory neurons, Rod photoreceptor cells, Inhibitory neurons, Oligodendrocyte precursor cells, Cone photoreceptor cells, Oligodendrocytes)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (AF22, NTERA-2, RT4, SCLC-21H, SH-SY5Y)

Interaction

AP-3 associates with the BLOC-1 complex (By similarity). Adaptor protein complex 3 (AP-3) is a heterotetramer composed of two large adaptins (delta-type subunit AP3D1 and beta-type subunit AP3B1 or AP3B2), a medium adaptin (mu-type subunit AP3M1 or AP3M2) and a small adaptin (sigma-type subunit APS1 or AP3S2).

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