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APBB1IP

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For Research Use Only. Not For Clinical Use.


Background

Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.
Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Microglial cells, dendritic cells, NK-cells, T-cells, Kupffer cells, Macrophages, B-cells)

Immune cell specificity

Immune cell enhanced (neutrophil)

Cell line specificity

Cell line enhanced (Daudi, MOLT-4, REH, U-698)

Interaction

Interacts, through the N-terminal Pro-rich region, with the WW domain of APBB1. Interacts with RAP1A, PFN1, TLN1, VASP, VCL and ENAH.

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