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APOBEC3F
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- Chicken Anti-Human APOBEC3F Polyclonal IgY (BRD-1190MZ)
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- Species Reactivity: N/A
- Type: Chicken antibody
- Application: N/A
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For Research Use Only. Not For Clinical Use.
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified.
Protein class
Enzymes
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (Karpas-707)
Interaction
Interacts with APOBEC3G in an RNA-dependent manner (PubMed:16699599). Interacts with AGO1, AGO2 and AGO3 (PubMed:22915799). (Microbial infection) Interacts with HIV-1 Vif (PubMed:15152192, PubMed:23001005). In the absence of Vif protein, specifically packaged into HIV-1 virions (PubMed:15152192).
Molecular function
Hydrolase
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