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ARHGEF16
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For Research Use Only. Not For Clinical Use.
Although the specific function of this protein is not known yet, it is thought to be involved in protein-protein and protein-lipid interactions.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Distal enterocytes, Proximal enterocytes, Paneth cells, Gastric mucus-secreting cells, Extravillous trophoblasts, Intestinal goblet cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (CAPAN-2, MCF7, OE19, SK-BR-3)
Interaction
Interacts with ELMO2, EPHA2, RAC1 and RHOG; mediates activation of RAC1 by EPHA2. Interacts with TAX1BP3 (via PDZ domain). May interact with CDC42; stimulated by HPV16 E6.
Molecular function
Guanine-nucleotide releasing factor
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