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ARMCX1

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For Research Use Only. Not For Clinical Use.


Background

This gene encodes a member of the ALEX family of proteins and may play a role in tumor suppression. The encoded protein contains a potential N-terminal transmembrane domain and two Armadillo (arm) repeats. Other proteins containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is closely localized with other family members, including ALEX2 and ALEX3, on the X chromosome.
Predicted location

Membrane

Single cell type specificity

Low cell type specificity

Immune cell specificity

Immune cell enhanced (myeloid DC)

Cell line specificity

Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+ SV40 Large T+ RasG12V, LHCN-M2, RH-30)

Interaction

Interacts with MIRO1.

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