Anti-ASMT Recombinant Antibody Products

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Anti-ASMT Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs offers highly specialized recombinant antibodies against ASMT, developed to support and enhance the progress of biomedical research. Through advanced technological platforms and strict quality control processes, we produce reagents that consistently meet demanding research standards for accuracy and performance. Our broad catalog reflects a dedication to delivering dependable, high-quality solutions that bring tangible value to scientific investigations. In addition to our product excellence, we provide expert technical support tailored to assist researchers throughout every phase of their projects. By working with Creative Biolabs, you gain access to innovative antibody technologies and a committed partner focused on advancing your scientific goals.

ASMT: A Vital Regulator in Sleep Mood and Neurodegenerative Disorders

ASMT is a key enzyme involved in the final step of melatonin biosynthesis, and its dysfunction has been increasingly associated with a range of neurological and psychiatric conditions. Altered enzymatic activity can disrupt circadian rhythm regulation, which plays a critical role in sleep disorders, particularly insomnia and delayed sleep phase syndrome. Impaired melatonin production has also been linked to mood disorders such as depression and bipolar disorder, where disruptions in the sleep-wake cycle and hormonal balance contribute to symptom severity. In autism spectrum disorders, genetic variants affecting this enzyme’s function are believed to contribute to abnormal melatonin levels, which may influence behavioral symptoms and sleep disturbances commonly observed in affected individuals. Additionally, the enzyme’s role in oxidative stress regulation and neuroprotection suggests its relevance in neurodegenerative diseases, including Alzheimer’s and Parkinson’s, where melatonin has been studied for its antioxidant and mitochondrial-stabilizing properties. Continued research into this enzyme’s role in brain function and systemic biological rhythms may offer promising avenues for therapeutic intervention across multiple disorders linked to melatonin imbalance.

Alternative Names

Complement Acetylserotonin O-Methyltransferase; Hydroxyindole O-Methyltransferase; HIOMT; Acetylserotonin Methyltransferase (Y Chromosome); Acetylserotonin N-Methyltransferase; EC 2.1.1.4; HIOMTY; ASMTY

Background

This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene.

Anti-ASMT rAb Products

Our anti-ASMT recombinant antibodies are designed to advance your research through reliable performance and consistent quality. We combine rigorously validated products with expert technical support to help overcome experimental challenges. Whether you're working on basic research or therapeutic development, our solutions aim to simplify your workflow while maintaining high standards. Additional customization options are available to meet specific project requirements.

Customer Reviews

Excellent

Ho**s
Rabbit Anti-ASMT Recombinant Antibody (clone DS266AB) (CAT#: MOR-0266)

We used the Rabbit Anti-ASMT Recombinant Antibody for Western blot analysis on human pineal gland lysates. The antibody showed clear, specific bands with very low background, which made interpretation straightforward. It integrated well with our existing protocol and didn’t require much optimization. Signal intensity was strong and reproducible across different experiments. Overall, a dependable reagent that helped us validate ASMT expression in our tissue samples without any technical issues.

03/Feb/2024

Excellent

I**go
Rabbit Anti-ASMT Recombinant Antibody (clone DS266AB) (CAT#: MOR-0266)

This rabbit anti-ASMT antibody worked great in my WB experiments with HEK293 and HeLa cell lysates. Showed sharp bands without cross-reactivity. Tried IHC-P on mouse liver tissue too—excellent specificity, minimal background. Required no optimization for dilution. Definitely recommend for ASMT detection in both cell and tissue samples.

09/Sep/2024

rAb Production

Leveraging years of experience in recombinant antibody engineering, we provide rigorously optimized antibodies with reliable performance. Our streamlined development process balances speed with quality control, delivering consistent results without compromising standards. This approach helps researchers obtain dependable reagents efficiently.

Featured Anti- ASMT Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-ASMT recombinant antibody production.

Fig.2 Gram-scale anti-ASMT recombinant antibody production.

rAb Modalities

Creative Biolabs specializes in high-performance recombinant antibodies for diverse research applications. Our team leverages advanced antibody engineering techniques to deliver reliable products, along with customized solutions tailored to your specific needs. We focus on providing tools that enhance experimental outcomes while maintaining rigorous quality standards.

Fig.3 Full Length Anti-ASMT Recombinant Antibody Production and Modalities.

For more details about ASMT or assistance with your experiments, please contact us by phone or email. Our technical team is available to help optimize protocols, troubleshoot issues, or provide product-specific guidance. Contact us today to discuss how we can support your research goals.