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ASMT

This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene.
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Theca cells, Alveolar cells type 2, Excitatory neurons, Oligodendrocytes, Inhibitory neurons, Early spermatids, Extravillous trophoblasts)

Immune cell specificity

Immune cell enhanced (naive B-cell)

Cell line specificity

Not detected

Interaction

Homodimer.

Molecular function

Methyltransferase, Transferase

More Types Infomation

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