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AVPR1B
Anti-AVPR1B Recombinant Antibody Products
- Recombinant Anti-human AVPR1B Antibody Fab Fragment (MOB-81-F(E))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IP, RIA, FuncS
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- Recombinant Anti-human AVPR1B Antibody scFv Fragment (MOB-81-S(P))
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- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: WB, IF, FuncS
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
Protein class
FDA approved drug targets, G-protein coupled receptors, Transporters
Predicted location
Membrane
Single cell type specificity
Not detected
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Molecular function
G-protein coupled receptor, Receptor, Transducer
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