B cell lymphoma BCL1 Idiotype & CD3
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For Research Use Only. Not For Clinical Use.
Background
The Id of the surface Ig of malignant B lymphocytes is a tumor-specific Ag.
In immunology, the CD3 (cluster of differentiation 3) T-cell co-receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ζ-chain to generate an activation signal in T lymphocytes. The TCR, ζ-chain, and CD3 molecules together comprise the TCR complex.