TRX4

Name: TRX4
SKU: Gly-002CL
Rating: 5 (1 reviews)

CAT#: Gly-002CL

TRX4 is a monoclonal antibody that binds to a receptor found on all T cells called CD3, which is involved in normal T cell signaling. TRX4 is believed to inhibit the function of autoreactive T cells, which are important in propagating autoimmune diseases, while inducing regulatory T cell pathways that promote immunological tolerance and inhibit autoreactive disease activity. Tolerx is developing TRX4 to treat patients with type 1 diabetes, psoriasis and other autoimmune diseases such as rheumatoid arthritis.

Specifications

Type
Small Molecule

Mechanism of action
TRX4 is a monoclonal antibody that binds to a receptor found on all T cells called CD3, which is involved in normal T cell signaling. TRX4 is believed to inhibit the function of autoreactive T cells, which are important in propagating autoimmune diseases, while inducing regulatory T cell pathways that promote immunological tolerance and inhibit autoreactive disease activity.

References

Synonyms
Otelixizumab

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for Gly-002CL. Click the button above to contact us or submit your feedback about this product.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Datasheet

Datasheet - Gly-002CL.pdf

MSDS

MSDS - Gly-002CL.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

See other products for "CD3"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
TAB-0365CL	Anti-Mouse CD3 Recombinant Antibody (Dow2)	FC, IHC
TAB-0416CL	Mouse Anti-CD3 Recombinant Antibody (TAB-0416CL)	FC, IB, ELISA
TAB-0365CL-S(P)	Anti-Mouse CD3 Recombinant Antibody scFv Fragment (Dow2)	IP, IB, FuncS
TAB-0416CL-S(P)	Mouse Anti-CD3 Recombinant Antibody scFv Fragment (TAB-0416CL-S(P))	IB, ELISA, FC, FuncS
TAB-0422CL-S(P)	Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-0422CL-S(P))	ELISA	Mouse scFv

CAT	Product Name	Application	Type
TAB-0418CL-F(E)	Humanized Anti-Human CD3 Recombinant Antibody Fab Fragment	ELISA, FC, FuncS	Humanized Antibody
TAB-075LC	Human Anti-CD3 Recombinant Antibody (TAB-075LC)	ELISA, FC	Humanized antibody
TAB-076LC	Human Anti-CD3 Recombinant Antibody (TAB-076LC)	ELISA, FC, FuncS	Human IgG1, κ
TAB-077LC	Human Anti-CD3 Recombinant Antibody (TAB-077LC)	ELISA, FC, FuncS	Human IgG1, κ
TAB-078LC	Human Anti-CD3 Recombinant Antibody (TAB-078LC)	ELISA, FC, FuncS	Human IgG1, κ

CAT	Product Name	Application	Type
TAB-071LC	Anti-Human CD3 Recombinant Antibody	ELISA	Chimeric antibody (mouse/human)
TAB-072LC	Chimeric Anti-Human CD3 Recombinant Antibody	ELISA	Chimeric antibody (mouse/human)
TAB-072LC-S(P)	Chimeric Anti-Human CD3 Recombinant Antibody scFv Fragment	ELISA	Chimeric antibody (mouse/human)
TAB-071LC-F(E)	Anti-Human CD3 Recombinant Antibody Fab Fragment	ELISA	Chimeric antibody (mouse/human)
TAB-072LC-F(E)	Chimeric Anti-Human CD3 Recombinant Antibody Fab Fragment	ELISA	Chimeric antibody (mouse/human)

CAT	Product Name	Application	Type
NEUT-339CQ	Mouse Anti-CD3 Recombinant Antibody (clone SPV-T3b)	FC, Block, IHC-Fr, IF, WB	Mouse IgG2a
NEUT-340CQ	Mouse Anti-CD3 Recombinant Antibody (clone UCHT1)	FC, IHC-Fr, IHC-P, ICC, IP, WB, Activ, Block	Mouse IgG1, κ

CAT	Product Name	Application	Type
FAMAB-0053-YC-S(P)	Mouse Anti-CD3 Recombinant Antibody (clone G3(3)); scFv Fragment	FC, IHC	Mouse scFv
FAMAB-0043CQ-S(P)	Mouse Anti-CD3 Recombinant Antibody (clone 898H2-6-15); scFv Fragment	FuncS	Mouse scFv
FAMAB-0044CQ-S(P)	Mouse Anti-CD3 Recombinant Antibody (clone FN18); scFv Fragment	WB, FC, FuncS	Mouse scFv
HPAB-0441-YJ-S(P)	Mouse Anti-CD3 Recombinant Antibody (clone m3E3); scFv Fragment	ELISA, FC	Mouse scFv
HPAB-0442-YJ-S(P)	Mouse Anti-CD3 Recombinant Antibody (clone hc3E3); scFv Fragment	ELISA, FC	Mouse scFv

CAT	Product Name	Application	Type
HPAB-0667LY	Mouse Anti-CD3 Recombinant Antibody (HPAB-0667LY)	ELISA, FC	Mouse IgG1
HPAB-0668LY	Mouse Anti-CD3 Recombinant Antibody (HPAB-0668LY)	ELISA, FC	Mouse IgG1
HPAB-0669LY	Mouse Anti-CD3 Recombinant Antibody (HPAB-0669LY)	ELISA, FC	Mouse IgG1
HPAB-0670LY	Mouse Anti-CD3 Recombinant Antibody (HPAB-0670LY)	ELISA, FC	Mouse IgG1
HPAB-0671LY	Mouse Anti-CD3 Recombinant Antibody (HPAB-0671LY)	ELISA, FC	Mouse IgG1

CAT	Product Name	Application	Type
HPAB-0667LY-F(E)	Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0667LY-F(E))	ELISA, FC	Mouse Fab
HPAB-0668LY-F(E)	Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0668LY-F(E))	ELISA, FC	Mouse Fab
HPAB-0669LY-F(E)	Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0669LY-F(E))	ELISA, FC	Mouse Fab
HPAB-0670LY-F(E)	Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0670LY-F(E))	ELISA, FC	Mouse Fab
HPAB-0671LY-F(E)	Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0671LY-F(E))	ELISA, FC	Mouse Fab

CAT	Product Name	Application	Type
HPAB-M0378-YC	Recombinant Llama Anti-CD3 Single Domain Antibody (HPAB-M0378-YC)	ELISA, FC	Llama VHH
HPAB-M0379-YC	Recombinant Llama Anti-CD3 Single Domain Antibody (HPAB-M0379-YC)	ELISA, FC	Llama VHH
HPAB-1029WJ	Recombinant Camelid Anti-CD3 Single Domain Antibody	ELISA	Camelid VHH

CAT	Product Name	Application	Type
VS-0724-XY16	Human Anti-CD3 Agonistic Antibody (VS-0724-XY16)	ELISA, Agonistic assays	Human IgG1

CAT	Product Name	Application	Type
VS-1024-XY89	Mouse Anti-NHP CD3 Recombinant Antibody (clone SK7)	IHC, FC	Mouse IgG1, kappa

CAT	Product Name	Application	Type
VS-0125-FY56	Human Anti-CD3 (clone YTH 12.5) scFv-Fc Chimera	ELISA, FC	Human IgG1, scFv-Fc

CAT	Product Name	Application	Type
VS-0325-XY360	Anti-CD3 Immunohistochemistry Kit	IHC

Specific Inquiry

Size:

Conjugation:

Endotoxin:

Purity:

Add to compare

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 1 Anti-ERBB2 Recombinant Antibody (Margetuximab) (TAB-761) in SPR

Anti-ERBB2 Recombinant Antibody (Margetuximab) (CAT# TAB-761)
Application: IF, IP, Neut, FuncS, ELISA, FC, WB

Figure 5 Anti-Human Mesothelin Recombinant Antibody (TAB-201) in HPLC

Anti-Human Mesothelin Recombinant Antibody (TAB-201) (CAT# TAB-201)
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC

Figure 2 Selectin P Recombinant Antibody (TAB-246) in ELISA

Anti-Human selectin P Recombinant Antibody (Inclacumab) (CAT# TAB-246)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC

Figure 1 Anti-Human ERBB3 Recombinant Antibody (TAB-H47) in SDS-PAGE

Humanized Anti-Human ERBB3 Recombinant Antibody (TAB-H47) (CAT# TAB-H47)
Application: ELISA, Inhib

Figure 3 Anti-Human IL4 Recombinant Antibody (TAB-221) in DB

Anti-Human IL4 Recombinant Antibody (TAB-221) (CAT# TAB-221)
Application: WB, ELISA, FC, IP, FuncS, IF, Neut

Figure 2 Chimeric (mouse/Human) Anti-TNFRSF8 Recombinant Antibody (TAB-153) in ELISA

Chimeric (Mouse/Human) Anti-TNFRSF8 Recombinant Antibody (TAB-153) (CAT# TAB-153)
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC

Figure 1 Anti-histone Antibody-Cytokine Fusion Protein, IgG-IL12 (ACFP-SH113) in ELISA

Anti-histone Antibody-Cytokine Fusion Protein, IgG (NHS76)-IL12 (CAT# ACFP-SH113)
Application:

Figure 1 Anti-Human CD200R Protein Antibody in ELISA

Human Anti-CD200R1 Recombinant Antibody (clone OX108) (CAT# PABC-020)
Application: WB, FuncS

Figure 4 Anti-Human CEACAM5 Recombinant Antibody (PABL-496) in ELISA

Recombinant Mouse Anti-HCV E2 Antibody (AP33) (CAT# PABL-496)
Application: FC, Neut, FuncS

Figure 6 Anti-LAM Recombinant Antibody (PABW-158, lot#CB2206LX02P6) in SEC-HPLC

Mouse Anti-LAM Recombinant Antibody (clone CS-35) (CAT# PABW-158)
Application: ELISA, IF, FC

Figure 2 Anti-CD3 Recombinant Antibody (TAB-0416CL-F(E)) in HPLC

Mouse Anti-CD3 Recombinant Antibody Fab Fragment (TAB-0416CL-F(E)) (CAT# TAB-0416CL-F(E))
Application: IB, ELISA, FC, FuncS

Figure 4 Anti-Human CEACAM5 Recombinant Antibody (TAB-408LC) in ELISA

Anti-Human CEACAM5 Recombinant Antibody (A5B7) (CAT# TAB-408LC)
Application:

Figure 2 Anti-Human TfR Antibody (TAB-611CT) in WB

Humanized Anti-TFRC Recombinant Antibody (TAB-611CT) (CAT# TAB-611CT)
Application: ELISA

Figure 3 Anti-HIV-1 clade B gp120 Recombinant Antibody (MRO-022LC) in ELISA

Anti-HIV-1 clade B gp120 Recombinant Antibody (A32) (CAT# MRO-022LC)
Application: WB

Figure 4 Rat Anti-CD38 Recombinant Antibody (NEUT-349CQ) in ELISA

Rat Anti-CD38 Recombinant Antibody (clone NIMR-5) (CAT# NEUT-349CQ)
Application: Neut, FC, IHC-Fr, IP, BA

Figure 2 Mouse Anti-MCAM Recombinant Antibody (HPAB-0031-YJ) in WB

Mouse Anti-MCAM Recombinant Antibody (clone AA98) (CAT# HPAB-0031-YJ)
Application: ELISA, FC, Inhib, IHC-Fr, WB, IP

Figure 2 Human Anti-HLA-DR4 Recombinant Antibody (HPAB-0826-FY) in HPLC

Human Anti-HLA-DR4/GAD-555-567 Recombinant Antibody (clone G3H8) (CAT# HPAB-0826-FY)
Application: FC

Figure 2 Recombinant Mouse Anti-Id (Idiotype) Antibody (HPAB-0644-WJ) in HPLC

Recombinant Mouse Anti-Id (Idiotype) Antibody (Ganglidiomab) (CAT# HPAB-0644-WJ)
Application: ELISA, WB

Figure 1 Mouse Anti-T7 RNA Polymerase Antibody (CBL-C001) (MOB-400CQ) in ELISA

Mouse Anti-T7 RNA Polymerase Antibody (CBL-C001) (CAT# MOB-400CQ)
Application: ELISA, WB

Figure 2 Mouse Anti-Anti-HIV-1 antibody VRC01 Anti-idiotype Antibody (PABJ-0191) in HPLC

Mouse Anti-Anti-HIV-1 antibody VRC01 Anti-idiotype Antibody (clone iv8) (CAT# PABJ-0191)
Application: ELISA, Vaccine, FuncS

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.