TRX4 (CAT#: Gly-002CL)
TRX4 is a monoclonal antibody that binds to a receptor found on all T cells called CD3, which is involved in normal T cell signaling. TRX4 is believed to inhibit the function of autoreactive T cells, which are important in propagating autoimmune diseases, while inducing regulatory T cell pathways that promote immunological tolerance and inhibit autoreactive disease activity. Tolerx is developing TRX4 to treat patients with type 1 diabetes, psoriasis and other autoimmune diseases such as rheumatoid arthritis.
Specific Inquiry
Specifications
- Type
- Small Molecule
- Mechanism of action
- TRX4 is a monoclonal antibody that binds to a receptor found on all T cells called CD3, which is involved in normal T cell signaling. TRX4 is believed to inhibit the function of autoreactive T cells, which are important in propagating autoimmune diseases, while inducing regulatory T cell pathways that promote immunological tolerance and inhibit autoreactive disease activity.
References
- Synonyms
- Otelixizumab
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD3"
Chimeric Antibody
| CAT | Product Name | Application | Type |
| TAB-0417CL | Chimeric Anti-Human CD3 Recombinant Antibody | ELISA, FC, FuncS | Chimeric (mouse/human) |
| TAB-0417CL-S(P) | Chimeric Anti-Human CD3 Recombinant Antibody scFv Fragment | ELISA, FC, FuncS | Chimeric (mouse/human) |
| TAB-0417CL-F(E) | Chimeric Anti-Human CD3 Recombinant Antibody Fab Fragment | ELISA, FC, FuncS | Chimeric (mouse/human) |
| TAB-071LC-S(P) | Anti-Human CD3 Recombinant Antibody scFv Fragment | ELISA | Chimeric antibody (mouse/human) |
| TAB-072LC-S(P) | Chimeric Anti-Human CD3 Recombinant Antibody scFv Fragment | ELISA | Chimeric antibody (mouse/human) |
Humanized Antibody
| CAT | Product Name | Application | Type |
| TAB-0418CL-S(P) | Anti-Human CD3 Recombinant Antibody scFv Fragment | ELISA, FC, FuncS | Humanized Antibody |
| TAB-0418CL-F(E) | Humanized Anti-Human CD3 Recombinant Antibody Fab Fragment | ELISA, FC, FuncS | Humanized Antibody |
| TAB-075LC-S(P) | Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-075LC-S(P)) | ELISA | Human scFv |
| TAB-076LC-S(P) | Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-076LC-S(P)) | ELISA | Human scFv |
| TAB-077LC-S(P) | Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-077LC-S(P)) | ELISA | Human scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
| TAB-070LC-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-070LC-F(E)) | ELISA | Mouse Fab |
| TAB-073LC-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-073LC-F(E)) | ELISA | Mouse Fab |
| TAB-074LC-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-074LC-F(E)) | ELISA | Mouse Fab |
| TAB-097LC-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-097LC-F(E)) | ELISA, SPR | Mouse Fab |
| TAB-099LC-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-099LC-F(E)) | ELISA, SPR | Mouse Fab |
Blocking Antibody
| CAT | Product Name | Application | Type |
| NEUT-339CQ | Mouse Anti-CD3 Recombinant Antibody (clone SPV-T3b) | FC, Block, IHC-Fr, IF, WB | Mouse IgG2a |
| NEUT-340CQ | Mouse Anti-CD3 Recombinant Antibody (clone UCHT1) | FC, IHC-Fr, IHC-P, ICC, IP, WB, Activ, Block | Mouse IgG1, κ |
Recombinant Antibody
| CAT | Product Name | Application | Type |
| FAMAB-0053YC | Mouse Anti-CD3 Recombinant Antibody (clone G3(3)) | FC, IHC | Mouse IgG |
| FAMAB-0043CQ | Mouse Anti-CD3 Recombinant Antibody (clone 898H2-6-15) | ELISA, FuncS | Mouse IgG2a, κ |
| FAMAB-0044CQ | Mouse Anti-CD3 Recombinant Antibody (clone FN18) | ELISA, WB, FC, FuncS | Mouse IgG, κ |
| HPAB-1793LY | Human Anti-CD3 Recombinant Antibody (HPAB-1793LY) | ELISA | Human IgG |
| FN-205CQ | Mouse Anti-CD3 Recombinant Antibody (clone CBL-1337) | FC, FuncS, IHC, IF, IP | Mouse IgG3, κ |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
| FAMAB-0053-YC-F(E) | Mouse Anti-CD3 Recombinant Antibody (clone G3(3)); Fab Fragment | FC, IHC | Mouse Fab |
| HPAB-0667LY-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0667LY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0668LY-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0668LY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0669LY-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0669LY-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0670LY-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (HPAB-0670LY-F(E)) | ELISA, FC | Mouse Fab |
Single-domain Antibody
| CAT | Product Name | Application | Type |
| HPAB-M0378-YC | Recombinant Llama Anti-CD3 Single Domain Antibody (A30228) | ELISA, FC | Llama VHH |
| HPAB-M0379-YC | Recombinant Llama Anti-CD3 Single Domain Antibody (A30311) | ELISA, FC | Llama VHH |
| HPAB-1029WJ | Recombinant Camelid Anti-CD3 Single Domain Antibody | ELISA | Camelid VHH |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
| HPAB-0546-WJ-S(P) | Human Anti-CD3 Recombinant Antibody (clone HuM291); scFv Fragment | ELISA | Humanized scFv |
| HPAB-0441-YJ-S(P) | Mouse Anti-CD3 Recombinant Antibody (clone m3E3); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-0442-YJ-S(P) | Mouse Anti-CD3 Recombinant Antibody (clone hc3E3); scFv Fragment | ELISA, FC | Mouse scFv |
| HPAB-1526WJ-S(P) | Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (clone 1D10) | ELISA, WB, FC | Mouse scFv |
| HPAB-1527WJ-S(P) | Human Anti-CD3 Recombinant Antibody; scFv Fragment (clone h1D10) | ELISA, WB, FC | Human scFv |
Customer Reviews and Q&As
Submit a review or a question
Thare are currently no Customer reviews or questions for Gly-002CL. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
* Abbreviations
3D IHC3D Immunohistochemistry
ActivActivation
AgonistAgonist
ApopApoptosis
BABioassay
BIBioimaging
BlockBlocking
Cell ScreeningCell Screening
SeparationCell Separation
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CostimCostimulation
CytCytotoxicity
DepletionDepletion
DBDot Blot
EMElectron Microscopy
ELISAEnzyme-linked Immunosorbent Assay
ELISPOTEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination
REImmunohistology - Resin Sections
IPImmunoprecipitation
IRMAImmunoradiometric Assay
SHIn situ hybridization
InhibInhibition
ICFCIntracellular Staining for Flow Cytometry
KO/KD-WBKnockout/Knockdown target confirmation by Western Blot
CyTOF®Mass Cytometry
MeDIPMethylated DNA Immunoprecipitation
PGProteogenomics
RIRadial Immunodiffusion
RIARadioimmunoassay
StimStimulation
SPRSurface Plasmon Resonance
WBWestern Blot
Send Inquiry
© 2022 Creative BioLabs. All Rights Reserved
