TRX4 (CAT#: Gly-002CL)
TRX4 is a monoclonal antibody that binds to a receptor found on all T cells called CD3, which is involved in normal T cell signaling. TRX4 is believed to inhibit the function of autoreactive T cells, which are important in propagating autoimmune diseases, while inducing regulatory T cell pathways that promote immunological tolerance and inhibit autoreactive disease activity. Tolerx is developing TRX4 to treat patients with type 1 diabetes, psoriasis and other autoimmune diseases such as rheumatoid arthritis.
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Specifications
- Type
- Small Molecule
- Mechanism of action
- TRX4 is a monoclonal antibody that binds to a receptor found on all T cells called CD3, which is involved in normal T cell signaling. TRX4 is believed to inhibit the function of autoreactive T cells, which are important in propagating autoimmune diseases, while inducing regulatory T cell pathways that promote immunological tolerance and inhibit autoreactive disease activity.
References
- Synonyms
- Otelixizumab
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Mouse Antibody
Chimeric Antibody
Humanized Antibody
Blocking Antibody
Recombinant Antibody
Fab Fragment Antibody
Single-domain Antibody
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0365CL | Anti-Mouse CD3 Recombinant Antibody (Dow2) | FC, IHC | |
| TAB-0416CL | Anti-Human CD3 Recombinant Antibody (OKT3) | FC, IB, ELISA | |
| TAB-0365CL-F(E) | Anti-Mouse CD3 Recombinant Antibody Fab Fragment (Dow2) | IP, IB, FuncS | |
| TAB-0416CL-F(E) | Anti-Human CD3 Recombinant Antibody Fab Fragment (OKT3) | IB, ELISA, FC, FuncS | |
| TAB-073LC-S(P) | Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-073LC-S(P)) | ELISA | Mouse scFv |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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