TRX4 (CAT#: Gly-002CL)
TRX4 is a monoclonal antibody that binds to a receptor found on all T cells called CD3, which is involved in normal T cell signaling. TRX4 is believed to inhibit the function of autoreactive T cells, which are important in propagating autoimmune diseases, while inducing regulatory T cell pathways that promote immunological tolerance and inhibit autoreactive disease activity. Tolerx is developing TRX4 to treat patients with type 1 diabetes, psoriasis and other autoimmune diseases such as rheumatoid arthritis.
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Specifications
- Type
- Small Molecule
- Mechanism of action
- TRX4 is a monoclonal antibody that binds to a receptor found on all T cells called CD3, which is involved in normal T cell signaling. TRX4 is believed to inhibit the function of autoreactive T cells, which are important in propagating autoimmune diseases, while inducing regulatory T cell pathways that promote immunological tolerance and inhibit autoreactive disease activity.
References
- Synonyms
- Otelixizumab
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Single Domain Antibodies
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IHC Kits & Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0365CL-S(P) | Anti-Mouse CD3 Recombinant Antibody scFv Fragment (Dow2) | IP, IB, FuncS | |
| TAB-0416CL-F(E) | Mouse Anti-CD3 Recombinant Antibody Fab Fragment (TAB-0416CL-F(E)) | IB, ELISA, FC, FuncS | |
| TAB-0422CL-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-0422CL-F(E)) | ELISA | Mouse Fab |
| TAB-070LC | Mouse Anti-CD3 Recombinant Antibody (TAB-070LC) | ELISA | Mouse IgG |
| TAB-540CT-F(E) | Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-540CT-F(E)) | ELISA, FC | Mouse Fab |
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