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BANK1

Anti-BANK1 Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1, 4, 5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Protein class

Disease related genes, Human disease related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enriched (B-cells)

Immune cell specificity

Group enriched (memory B-cell, naive B-cell)

Cell line specificity

Cell line enhanced (Daudi, HEL, HL-60, U-266/70)

Interaction

Interacts with LYN, ITPR1 and ITPR2.

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