+ Filter
Loading...
BBC3
Loading...Anti-BBC3 Products
- Rabbit Anti-BBC3 Recombinant Antibody (clone CBACN-468) (MRO-1298-CN)
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
Compare
- Rabbit Anti-BBC3 Polyclonal Antibody (MRO-2148-CN) (MRO-2148-CN)
-
- Species Reactivity: Human, Mouse
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
Compare
- Rabbit Anti-BBC3 Recombinant Antibody (VS3-WK1133) (VS3-WK1133)
-
- Derivation: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, ICC, IF, IHC, FC
Compare
-
- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IHC-F, IHC-P, ICC, IF
Compare
- Anti-BBC3 Immunohistochemistry Kit (VS-0525-XY702)
-
- Species Reactivity: Human
- Target: BBC3
- Application: IHC
Compare
- Anti-Mouse BBC3 Immunohistochemistry Kit (VS-0525-XY703)
-
- Species Reactivity: Human, Mouse, Rat
- Target: BBC3
- Application: IHC
Compare
More Infomation
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Suprabasal keratinocytes, Prostatic glandular cells, Basal keratinocytes, Basal squamous epithelial cells)
Immune cell specificity
Group enriched (basophil, neutrophil)
Cell line specificity
Cell line enhanced (HHSteC, NB-4)
Interaction
Interacts with MCL1 and BCL2A1 (By similarity). Interacts (via BH3 domain) with BCL2 (PubMed:11463391). Interacts with BCL2L1/BCL-XL (PubMed:23340338). Interacts (via BH3 domain) with NOL3/ARC (via CARD domain); this interaction prevents BBC3 association with BCL2 and results in CASP8 activation (By similarity).
More Types Infomation