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BTF3
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Anti-BTF3 Products
- Mouse Anti-BTF3 Recombinant Antibody (clone 739D6b) (MOB-1478MZ)
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: WB
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes the basic transcription factor 3. This protein forms a stable complex with RNA polymerase IIB and is required for transcriptional initiation. Alternative splicing results in multiple transcript variants encoding different isoforms. This gene has multiple pseudogenes.
Protein class
Plasma proteins
Predicted location
Intracellular
Single cell type specificity
Low cell type specificity
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Part of the nascent polypeptide-associated complex (NAC), which is a heterodimer of NACA and BTF3 (via NAC-A/B domains). NAC associates with ribosomes through the BTF3/NACB subunit. Both subunits can contact nascent polypeptide chains.
Molecular function
Chaperone
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