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C1QB
Loading...Anti-C1QB Products
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, ELISA, FC, IF, IHC
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- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: ICC, IHC-P, WB
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- Anti-C1QB Immunohistochemistry Kit (VS-0525-XY871)
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- Species Reactivity: Human
- Target: C1QB
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes