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CACNA1I
This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants.
Protein class
FDA approved drug targets, Plasma proteins, Transporters, Voltage-gated ion channels
Predicted location
Membrane
Single cell type specificity
Group enriched (Bipolar cells, Excitatory neurons, Inhibitory neurons)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (SK-BR-3, T-47d)
Interaction
Interacts with CATSPER1 and CATSPER2, leading to suppress T-type calcium channel activity.
Molecular function
Calcium channel, Ion channel, Voltage-gated channel
More Types Infomation
- Recombinant Mouse Anti-Human CACNA1I Antibody (MOB-1946MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, FC, IHC, IP
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For Research Use Only. Not For Clinical Use.