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CACNG5

Anti-CACNG5 Products
- Rabbit Anti-CACNG5 Polyclonal Antibody (MRO-1709-CN) (MRO-1709-CN)
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- Species Reactivity: Human, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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For Research Use Only. Not For Clinical Use.
Background
CACNG5 (Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 5) is a Protein Coding gene. Diseases associated with CACNG5 include Bipolar Disorder and Schizophrenia. Among its related pathways are Cardiac conduction and NFAT and Cardiac Hypertrophy. Gene Ontology (GO) annotations related to this gene include voltage-gated calcium channel activity and ion transmembrane transporter activity. An important paralog of this gene is CACNG7.
Protein class
FDA approved drug targets
Predicted location
Membrane
Single cell type specificity
Cell type enriched (Oligodendrocyte precursor cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Not detected
Interaction
The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma. Acts as an auxiliary subunit for AMPA-selective glutamate receptors (AMPARs). Found in a complex with GRIA1, GRIA2, GRIA3, GRIA4, CNIH2, CNIH3, CACNG2, CACNG3, CACNG4, CACNG7 and CACNG8. Interacts with GRIA1, GRIA2, GRIA3 and GRIA4 (By similarity).
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