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CAMKK2

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For Research Use Only. Not For Clinical Use.


This gene encodes a class I protein methyltransferase that acts in the formation of trimethyllysine in calmodulin. The protein contains a AdoMet-binding motif and may play a role in calcium-dependent signaling. [provided by RefSeq, Sep 2012]
Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular, Membrane (different isoforms)

Single cell type specificity

Cell type enhanced (Late spermatids, Excitatory neurons, Horizontal cells)

Immune cell specificity

Group enriched (eosinophil, intermediate monocyte, non-classical monocyte, neutrophil, classical monocyte, myeloid DC)

Cell line specificity

Low cell line specificity

Interaction

Interacts with calmodulin.

Molecular function

Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase

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