Anti-CAMP Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs is here to help with your immunology and host defense research. Our anti-CAMP recombinant antibodies offer high specificity and performance for one of the central players in antimicrobial defense. Cathelicidin Antimicrobial Peptide (CAMP) is the precursor to the human antimicrobial peptide LL-37, a key molecule of the innate immune system. Our validated antibodies are powerful tools for host defense research, inflammation, and the role of antimicrobial peptides in disease, including psoriasis and rosacea.

CAMP: The Precursor to the Human Cathelicidin LL-37

The Cathelicidin Antimicrobial Peptide (CAMP) is the single cathelicidin member of the antimicrobial peptide family found in humans. Cathelicidins are synthesized as 18 kDa precursor proteins called hCAP-18, which are found in high levels in neutrophils and epithelial cells at barrier surfaces. CAMP itself, as the precursor protein, is not active. In the presence of infection or inflammation, proteases such as proteinase 3 cleave the C-terminal end of the precursor protein to release the active 37-amino acid peptide LL-37. LL-37 is a broad-spectrum, potent antimicrobial that kills bacteria, viruses, and fungi by disrupting membrane integrity. The peptide is also a potent immunomodulatory molecule, with roles in inflammation, wound repair, and angiogenesis.

Alternative Names

Cathelicidin Antimicrobial Peptide; 18 KDa Cationic Antimicrobial Protein; CAP-18; FALL39; CAP18; FALL-39

Background

CAMP (Cathelicidin Antimicrobial Peptide) is a Protein Coding gene. Diseases associated with CAMP include Rosacea and Mycobacterium Marinum. Among its related pathways are Innate Immune System and Defensins.

Anti-CAMP rAb Products

Creative Biolabs' anti-CAMP recombinant antibodies are designed with rigor to deliver specificity and performance. We offer recombinant antibodies that are specific for the full-length hCAP-18 precursor, as well as those that are specific for the active, cleaved form of the molecule, LL-37. This allows our customers to study the stored form as well as the active peptide separately. All of our antibodies are optimized for ELISA, Western Blot, and IHC, and will provide the consistent performance needed for detailed studies of this molecule.

Table 1. Featured anti-CAMP recombinant antibody products at Creative Biolabs.

Customer Reviews

rAb Production

Creative Biolabs has access to and uses the most advanced antibody production platforms to ensure our products have the necessary fidelity to support cutting edge applications, including immunology. Our anti-CAMP and anti-LL-37 recombinant antibodies are expressed in systems that have been optimized to ensure that the final products will specifically recognize their intended targets. These antibody platforms deliver rAbs that are highly specific and active for your experiments.

Featured Anti-CAMP Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-CAMP recombinant antibody production.

Fig.2 Gram-scale anti-CAMP recombinant antibody production.

rAb Modalities

Creative Biolabs is driven by the goal of enabling scientific research through flexible antibody solutions. Our anti-CAMP recombinant antibodies are available as matched pairs for ELISA as well as a variety of formats to support your experimental needs. Help us empower researchers around the world to study this important antimicrobial peptide.

Fig.3 Full-length anti-CAMP recombinant antibody production and modalities.

Explore the intricacies of innate immune defense with Creative Biolabs' high specificity anti-CAMP recombinant antibodies. Choose from a validated portfolio with the consistency and rigor needed to investigate this key molecule in host defense. Place your research on solid ground, and contact our scientific team today.