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    CAT

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    For Research Use Only. Not For Clinical Use.


    Background

    cat, or Chloramphenicol acetyltransferase (CAT), is an enzyme that catalyzes the transfer of an acetyl group from acetyl-CoA to chloramphenicol, rendering the antibiotic inactive. CAT is a common bacterial resistance mechanism and is widely used as a reporter gene in molecular biology to monitor gene expression in various organisms.
    Protein class

    Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins

    Predicted location

    Intracellular

    Single cell type specificity

    Cell type enhanced (Erythroid cells, Hepatocytes, Proximal tubular cells)

    Immune cell specificity

    Immune cell enriched (eosinophil)

    Cell line specificity

    Cell line enhanced (HL-60, THP-1, U-937)

    Interaction

    Homotetramer.

    Molecular function

    Mitogen, Oxidoreductase, Peroxidase

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