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CCT2

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For Research Use Only. Not For Clinical Use.


Background

CCT2 (Chaperonin Containing TCP1 Subunit 2) is a Protein Coding gene. Diseases associated with CCT2 include Gallbladder Adenocarcinoma and Adenosquamous Carcinoma. Among its related pathways are Organelle biogenesis and maintenance and Innate Immune System. Gene Ontology (GO) annotations related to this gene include ubiquitin protein ligase binding and unfolded protein binding.
Protein class

Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Early spermatids, Spermatocytes)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Component of the chaperonin-containing T-complex (TRiC), a heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter (PubMed:20080638, PubMed:25467444). Interacts with PACRG (PubMed:14532270). Interacts with FLCN (PubMed:27353360). Interacts with DLEC1 (PubMed:33144677).

Molecular function

Chaperone

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