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CD101
Loading...Anti-CD101 Products
- Mouse Anti-CD101 Recombinant Antibody (clone CC38) (MOB-0639MZ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: FC, WB
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- Anti-CD101 Immunohistochemistry Kit (VS-0525-XY1114)
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- Species Reactivity: Human
- Target: CD101
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Plays a role as inhibitor of T-cells proliferation induced by CD3. Inhibits expression of IL2RA on activated T-cells and secretion of IL2. Inhibits tyrosine kinases that are required for IL2 production and cellular proliferation. Inhibits phospholipase C-gamma-1/PLCG1 phosphorylation and subsequent CD3-induced changes in intracellular free calcium. Prevents nuclear translocation of nuclear factor of activated T-cell to the nucleus. Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells. May be a marker of CD4(+) CD56(+) leukemic tumor cells.
Protein class
CD markers
Predicted location
Membrane
Single cell type specificity
Cell type enhanced (Macrophages, Kupffer cells, Sertoli cells, monocytes, T-cells, Skeletal myocytes, Oligodendrocyte precursor cells)
Immune cell specificity
Immune cell enhanced (eosinophil)
Cell line specificity
Cell line enriched (HMC-1)
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