CDC42EP2

Formats

Anti-CDC42EP2 Recombinant Antibody Products

Recombinant Mouse anti-Human CDC42EP2 Monoclonal antibody (EML1085) (MOB-0515CT)
- Species Reactivity: Human
- Application: WB
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For Research Use Only. Not For Clinical Use.

CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control. [provided by RefSeq, Aug 2011]

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Langerhans cells, Pancreatic endocrine cells, Ductal cells)

Immune cell specificity

Group enriched (neutrophil, intermediate monocyte, non-classical monocyte, classical monocyte)

Cell line specificity

Cell line enhanced (HHSteC, PC-3, U-2197)

Interaction

Interacts with RHOQ and CDC42 in a GTP-dependent manner, and with SEPT7.

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