Anti-CDK16 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs is an expert in neuroscience research and membrane trafficking. Our world-class anti-CDK16 recombinant antibodies will support your research as you study this non-canonical Cyclin-Dependent Kinase. CDK16 (PCTAIRE-1) is known to be important for regulation of membrane trafficking in neurons. Our top-quality anti-CDK16 rAbs have been carefully validated to work optimally in your applications and will be a powerful tool to study its role in synaptic plasticity, neuronal development, and links to psychiatric disease.

CDK16: A Regulator of Neuronal Trafficking

CDK16 (also known as PCTAIRE-1) is a non-canonical CDK that is significantly enriched in the central nervous system. While many of the classical CDKs are primarily involved in regulating the cell cycle, CDK16 does not appear to be as tightly linked to this process. Instead, CDK16 is thought to be involved in regulation of membrane trafficking, particularly vesicle and protein complex movement within neurons. This includes potential effects on synaptic function as well as regulation of protein transport up and down the axon. This highly specific expression pattern in the brain as well as its unique regulation of trafficking make this an attractive target for neurological drug development.

Alternative Names

Cyclin Dependent Kinase 16; Serine/Threonine-Protein Kinase PCTAIRE-1; Cell Division Protein Kinase 16; PCTAIRE-Motif Protein Kinase 1; EC 2.7.11.22; PCTAIRE1; PCTK1; Testis Secretory Sperm-Binding Protein Li 224n

Background

CDK16 (Cyclin Dependent Kinase 16) is a Protein Coding gene. Among its related pathways are DNA Damage and Signal transduction_PKA signaling. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDK17.

Anti-CDK16 rAb Products

Our recombinant anti-CDK16 antibodies have been designed for high specificity and performance. They are carefully validated to specifically detect the CDK16 protein. Our anti-CDK16 rAbs have been optimized for IHC on brain tissue sections to look at expression pattern as well as cellular fractionation studies using Western Blot to follow its interaction with membranes.
Table 1. Featured anti-CDK16 recombinant antibody products at Creative Biolabs.

Customer Reviews

rAb Production

Creative Biolabs has a state-of-the-art production infrastructure to ensure world-class products for discovery research. Our anti-CDK16 recombinant antibodies are produced in optimized systems to ensure that they recognize the native protein and thus result in a specific and active tool.

Featured Anti-CDK16 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-CDK16 recombinant antibody production.

Fig.2 Gram-scale anti-CDK16 recombinant antibody production.

rAb Modalities

Creative Biolabs is focused on the most advanced antibody technology to help drive scientific discovery. Our anti-CDK16 recombinant antibodies are available in a variety of customizable modalities to meet the needs of your experiments. No matter your project, Creative Biolabs has a tool to help advance your work in cancer biology.

Fig.3 Full-length anti-CDK16 recombinant antibody production and modalities.

Partner with Creative Biolabs to help investigate the uncharacterized functions of CDK16 with the help of our highly specific and validated recombinant antibodies. Whether you are looking at the regulation of CDK16 activity or working to define it as a novel therapeutic target, our product portfolio has the tools you need to discover. Contact one of our specialists today.