Anti-CDK17 Recombinant Antibody Products

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Anti-CDK17 Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs is at the forefront of cell signaling, providing premium anti-CDK17 recombinant antibodies. CDK17, a non-canonical Cyclin-Dependent Kinase (PCTAIRE-2), is a regulator of membrane transport and may be implicated in oncogenesis. Our high-quality antibodies are the perfect research tool to study its role in the secretory pathway and in disease.

CDK17: A Kinase in the Secretory Pathway

Cyclin-Dependent Kinase 17 (CDK17, PCTAIRE-2) is a non-classical CDK family member. Like CDK16, it does not regulate the cell cycle, but intracellular trafficking and secretion. CDK17 co-localizes with the Golgi and is thought to phosphorylate proteins involved in vesicular transport and protein processing. It is expressed in a more limited pattern than CDK16 and may have a role in regulating these processes in highly secretory cell types. As with many CDKs, misregulation of CDK17 is being examined as a potential contributor to tumorigenesis.

Alternative Names

CDK17; cyclin-dependent kinase 17; PCTK2; PCTAIRE2; PCTAIRE-motif protein kinase 2; cell division protein kinase 17; protein kinase cdc2-related PCTAIRE-2; serine/threonine-protein kinase PCTAIRE-2;

Background

The protein encoded by this gene belongs to the cdc2/cdkx subfamily of the ser/thr family of protein kinases. It has similarity to a rat protein that is thought to play a role in terminally differentiated neurons. Alternatively spliced transcript variants encoding different isoforms have been found.

Protein class

Enzymes, Metabolic proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Oligodendrocytes, Excitatory neurons)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Cell line enhanced (HUVEC TERT2, TIME)

Interaction

Found in a complex containing CABLES1, CDK16 and TDRD7. Interacts with TDRD7 (By similarity).

Molecular function

Kinase, Serine/threonine-protein kinase, Transferase

More Types Infomation

Anti-CDK17 rAb Products

Creative Biolabs’ anti-CDK17 recombinant antibodies are engineered for specificity and superior performance. Our anti-CDK17 rAbs are thoroughly validated to specifically detect the CDK17 protein with no cross-reactivity with other PCTAIRE family members. We optimize these antibodies for a range of applications, including immunofluorescence to visualize Golgi localization and Western Blot for protein detection. With these rAbs, researchers can rely on validated, reproducible tools for their cell biology studies.
Table 1. Featured anti-CDK17 recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
MOB-1586CT Recombinant Mouse anti-Human CDK17 Monoclonal antibody (0.O.600) Human Mouse IgG WB
MOR-0625 Hi-Affi™ Rabbit Anti-CDK17 Recombinant Antibody (clone DS625AB) Human Rabbit IgG ELISA, IHC-P, WB

Customer Reviews

Excellent
O**ra
Recombinant Mouse anti-Human CDK17 Monoclonal antibody (0.O.600)
The Creative Biolabs anti-CDK17 antibody was crucial for our study. We used it for immunofluorescence and it gave a really nice, crisp staining pattern on the Golgi apparatus.
11/Oct/2023

rAb Production

To meet the needs of specialized areas like cell biology, Creative Biolabs employs cutting-edge antibody production platforms. We use optimized systems for expression of our anti-CDK17 recombinant antibodies to ensure they will recognize native kinase and provide a specific and active tool.

Featured Anti-CDK17 Recombinant Antibody Production PlatformsFig.1 Milligram-scale. (Creative Biolabs Original)
Fig.1 Milligram-scale anti-CDK17 recombinant antibody production.

Fig.2 Gram-scale. (Creative Biolabs Original)Fig.2 Gram-scale anti-CDK17 recombinant antibody production.

rAb Modalities

Creative Biolabs is committed to fueling scientific breakthroughs and understands that flexibility is crucial to accommodate unique projects and applications. Our anti-CDK17 recombinant antibodies can be customized in a range of modalities, giving researchers the tools they need to explore this important enzyme.

Fig.3 CDK17 antibody production and modalities. (Creative Biolabs Original)Fig.3 Full-length anti-CDK17 recombinant antibody production and modalities.

Explore the intricacies of protein trafficking with Creative Biolabs’ anti-CDK17 recombinant antibodies. Our portfolio was designed with the rigorous validation and specificity that key cell biology studies demand. Place your trust in our expertise and build your studies on a foundation of excellence. Contact our scientific team today.

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