CDX1
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Loading...- Rabbit Anti-CDX1 Recombinant Antibody (clone JG38-50) (MRO-0348-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF
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- Mouse Anti-CDX1 Recombinant Antibody (VS3-FY2664) (VS3-FY2664)
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- Species Reactivity: Human, Mouse, Rat
- Type: Mouse IgG
- Application: WB
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- Anti-CDX1 Immunohistochemistry Kit (VS-0325-XY417)
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- Species Reactivity: Human, Mouse, Rat
- Target: CDX1
- Application: IHC
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- Anti-Human CDX1 Immunohistochemistry Kit (VS-0525-XY1350)
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- Species Reactivity: Human
- Target: CDX1
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.
Protein class
Transcription factors
Predicted location
Intracellular
Single cell type specificity
Group enriched (Distal enterocytes, Undifferentiated cells, Paneth cells, Proximal enterocytes, Intestinal goblet cells)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Group enriched (BJ hTERT+, SuSa)
Molecular function
Activator, Developmental protein, DNA-binding
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