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CGB7

Anti-CGB7 Products

Mouse Anti-CGB7 Recombinant Antibody (clone 20F6) (MOB-3221z)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG2a, κ
- Application: WB, ELISA
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Hi-Affi™ Rabbit Anti-CGB7 Recombinant Antibody (clone DS680AB) (MOR-0680)
- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, FC, IP
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For Research Use Only. Not For Clinical Use.

Background

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.

Predicted location

Secreted

Single cell type specificity

Group enriched (Syncytiotrophoblasts, Pancreatic endocrine cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced (BEWO, HaCaT, hTCEpi, U-251 MG)

Interaction

Heterodimer of a common alpha chain identical in LH, FSH, TSH and HCG and a unique beta chain distinct in each of the hormones and confers receptor and biological specificity.

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