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CHST2

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For Research Use Only. Not For Clinical Use.


This locus encodes a sulfotransferase protein. The encoded enzyme catalyzes the sulfation of a nonreducing N-acetylglucosamine residue, and may play a role in biosynthesis of 6-sulfosialyl Lewis X antigen.
Protein class

Metabolic proteins

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (NK-cells, Muller glia cells, Sertoli cells, Plasma cells, Theca cells)

Immune cell specificity

Group enriched (non-classical monocyte, NK-cell, intermediate monocyte)

Cell line specificity

Cell line enhanced (ASC diff, ASC TERT1, HEL, HHSteC, HMC-1, HSkMC, U-266/70)

Interaction

Homodimer; disulfide-linked. Homodimerization is not essential for enzyme activity.

Molecular function

Transferase

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