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CKS2

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For Research Use Only. Not For Clinical Use.


Background

CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS2 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects specialized role for the encoded protein.
Protein class

Cancer-related genes

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (Spermatocytes, Spermatogonia, Langerhans cells)

Immune cell specificity

Immune cell enhanced (plasmacytoid DC)

Cell line specificity

Low cell line specificity

Interaction

Forms a homohexamer that can probably bind six kinase subunits.

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