Anti-CLASP1 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs is your go-to provider for cell biology and oncology research with high-quality anti-CLASP1 recombinant antibodies. Cytoplasmic Linker Associated Protein 1 (CLASP1) is a critical microtubule-associated protein that regulates the dynamics of microtubules in mitosis and during cell migration. Our high-quality anti-CLASP1 antibodies are the perfect research tool to study its involvement in cell division, cancer progression, and neuronal development.

CLASP1: A Key Regulator of Microtubule Dynamics

Cytoplasmic Linker Associated Protein 1 (CLASP1) is a “plus-end tracking protein” (+TIP) that associates with the growing end of microtubules. It plays a vital role in stabilizing dynamic microtubules by promoting microtubule rescue (switching from shrinkage to growth) and anchoring the microtubules to specific sites, such as the cell cortex and chromosome kinetochores during mitosis. This activity is crucial for the formation of a functional mitotic spindle, chromosome segregation, and the establishment of cell polarity during cell migration. The protein is frequently dysregulated in cancers and is linked to genomic instability and increased metastatic potential.

Alternative Names

Cytoplasmic Linker Associated Protein 1; Multiple Asters Homolog 1; Protein Orbit Homolog 1; Multiple Asters 1; MAST1; Cytoplasmic Linker-Associated Protein 1; CLIP-Associating Protein 1; KIAA0622; HOrbit1

Background

CLASPs, such as CLASP1, are nonmotor microtubule-associated proteins that interact with CLIPs (e.g., CLIP170; MIM 179838). CLASP1 is involved in the regulation of microtubule dynamics at the kinetochore and throughout the spindle.

Anti-CLASP1 rAb Products

Creative Biolabs’ anti-CLASP1 recombinant antibodies are designed for maximum specificity. They are stringently validated to ensure detection of the CLASP1 protein only and is therefore an ideal tool to study its dynamic localization. Optimized for challenging applications such as immunofluorescence to visualize its association with the tips of microtubules and the mitotic spindle, and for Western Blot, our rAbs are the perfect choice to deliver consistent, high-quality results.

Table 1. Featured anti-CLASP1 recombinant antibody products at Creative Biolabs.

Customer Reviews

rAb Production

Creative Biolabs leverages cutting-edge production technologies to support cell biology research with high-quality recombinant antibodies. Our anti-CLASP1 rAbs are produced in optimized expression systems, which means they will accurately recognize the native protein and provide a highly specific, active research tool for your experiments.

Featured Anti-CLASP1 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-CLASP1 recombinant antibody production.

Fig.2 Gram-scale anti-CLASP1 recombinant antibody production.

rAb Modalities

Creative Biolabs is committed to advancing scientific discovery by providing a portfolio of customizable antibody solutions. Our anti-CLASP1 recombinant antibodies are available in a variety of modality formats that are customizable to meet your research needs, empowering researchers around the world to study this important cytoskeletal regulator.

Fig.3 Full-length anti-CLASP1 recombinant antibody production and modalities.

Explore CLASP1’s vital functions in cell division with the exceptional quality of Creative Biolabs’ recombinant antibodies. Our portfolio is characterized by high specificity and stringent validation, making them the perfect tools for your cancer and neuroscience research. Choose Creative Biolabs and our quality that leads to discovery. Contact one of our specialists today.