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CLTB
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- Chicken Anti-CLTB Polyclonal IgY (BRD-0131MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: indirect ELISA, WB
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- Chicken Anti-Clathrin Light Chain B Polyclonal IgY (BRD-1044MZ)
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- Species Reactivity: Human
- Type: Chicken antibody
- Application: ELISA, WB
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- Anti-CLTB Immunohistochemistry Kit (VS-0325-XY478)
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- Species Reactivity: Human
- Target: CLTB
- Application: IHC
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For Research Use Only. Not For Clinical Use.
Background
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Protein class
Plasma proteins, Transporters
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Pancreatic endocrine cells)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Cell line enhanced (HBEC3-KT, MCF7)
Interaction
Clathrin coats are formed from molecules containing 3 heavy chains and 3 light chains. Interacts (via N-terminus) with HIP1. Interacts with HIP1R.
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