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COX5B
Anti-COX5B Recombinant Antibody Products
- Recombinant Mouse Anti-Human COX5B Antibody (MOB-0717MZ)
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- Species Reactivity: Human
- Type: Mouse antibody
- Application: WB
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- AbPlus™ Anti-COX5B Magnetic Beads (VS-0724-YC207) (VS-0724-YC207)
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- Target: COX5B
- Target Species: Human
- Application: IP, Protein Purification
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For Research Use Only. Not For Clinical Use.
COX5B (Cytochrome C Oxidase Subunit 5B) is a Protein Coding gene. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Gene Expression. Gene Ontology (GO) annotations related to this gene include cytochrome-c oxidase activity.
Protein class
Metabolic proteins, Transporters
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Distal tubular cells, Cardiomyocytes, Proximal enterocytes)
Immune cell specificity
Low immune cell specificity
Cell line specificity
Low cell line specificity
Interaction
Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I1 (or COX4I2), COX5A, COX5B, COX6A1 (or COX6A2), COX6B1 (or COX6B2), COX6C, COX7A2 (or COX7A1), COX7B, COX7C, COX8A and NDUFA4, which are encoded in the nuclear genome (PubMed:30030519). The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)) (PubMed:28844695).
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