Anti-COX6A2 Recombinant Antibody Products
Loading...Anti-COX6A2 Products
+ Filter
Loading...- Recombinant Anti-Human COX6A2 Antibody (MOB-3800z)
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: ELISA, WB, FC, FuncS
Compare
- Recombinant Anti-Human COX6A2 Antibody Fab Fragment (MOB-3800z-F(E))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab
- Application: IF, FACS, FuncS
Compare
- Recombinant Anti-Human COX6A2 Antibody scFv Fragment (MOB-3800z-S(P))
-
- Derivation: Mouse
- Species Reactivity: Human
- Type: scFv
- Application: FC, ELISA, FuncS
Compare
View More Products
Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag
More Infomation
Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us
For Research Use Only. Not For Clinical Use.
Seeking solutions for your cardiovascular research? Creative Biolabs' premium anti-COX6A2 recombinant antibodies are here to help. COX6A2, the cardiac and muscle-specific isoform of a Complex IV subunit, is a crucial part of the heart's metabolic regulation. Creative's validated and high-quality anti-COX6A2 antibodies allow you to explore cardiac bioenergetics, mitochondrial disease, and stress-induced metabolic remodeling.
COX6A2: A Tissue-Specific Regulator of Complex IV
Cytochrome c Oxidase Subunit 6A, Isoform 2 (COX6A2) is the heart and skeletal muscle-specific isoform of the COX6A subunit of the Cytochrome C Oxidase (COX) complex (also known as Complex IV). This protein is a member of a family of metabolic switches that, like COX4I1, substitutes the ubiquitously expressed COX6A1 isoform in these tissues. The function of this complex is to promote ATP production through oxidative phosphorylation, and the expression of this unique isoform of COX6A is thought to fine-tune the activity of Complex IV in these metabolically active tissues, rendering it more efficient and giving these tissues their characteristic metabolic phenotype. Since this protein is only expressed in skeletal muscle and heart tissue, it makes an excellent endogenous marker of these tissues' metabolic identity.
Alternative Names
COX6A2; Cytochrome C Oxidase Subunit VIA-Muscle; COX6AH; Cytochrome C Oxidase Subunit 6A2, Mitochondrial; COXVIAH; COX6A; Cytochrome C Oxidase Polypeptide VIa-Heart; Cytochrome C Oxidase Subunit VIa Polypeptide 2; COX VIa-M
Background
Protein class
Disease related genes, Metabolic proteins, Potential drug targets, Transporters
Predicted location
Intracellular
Single cell type specificity
Cell type enriched (Cardiomyocytes)
Immune cell specificity
Immune cell enriched (NK-cell)
Cell line specificity
Cell line enriched (U-266/84)
Interaction
Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I1 (or COX4I2), COX5A, COX5B, COX6A1 (or COX6A2), COX6B1 (or COX6B2), COX6C, COX7A2 (or COX7A1), COX7B, COX7C, COX8A and NDUFA4, which are encoded in the nuclear genome (By similarity). The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)) (By similarity).
Molecular function
Oxidoreductase
More Types Infomation
Anti-COX6A2 rAb Products
Our anti-COX6A2 recombinant antibodies are engineered and validated to provide the best in specificity. Thoroughly validated to specifically recognize the COX6A2 isoform without cross-reactivity to the ubiquitous COX6A1, our rAbs are optimized for use in Western Blot of cardiac and muscle lysates as well as IHC. Creative Biolabs rAbs provide the specificity, activity, and consistency you need for reliable metabolic research.
Table 1. Featured anti-COX6A2 recombinant antibody products at Creative Biolabs.
| Cat. No. | Product Name | Target Species | Host Species | Applications |
| MOB-3800z | Recombinant Anti-Human COX6A2 Antibody | Human | Mouse IgG | ELISA, WB, FC, FuncS |
Customer Reviews
Excellent
Ron**ldRecombinant Anti-Human COX6A2 Antibody
We study muscle fiber type and this antibody has been a great tool to separate oxidative and glycolytic fibers by IHC. It's a very reliable antibody.
13/Sep/2024
rAb Production
Creative Biolabs employs the most advanced production platforms available to support the unique needs of cardiovascular research. Creative Biolabs' recombinant anti-COX6A2 antibodies are expressed in systems optimized for each target to ensure our antibodies specifically recognize their intended targets and that the final product is a highly specific and active antibody.
Featured Anti-COX6A2 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-COX6A2 recombinant antibody production.
Fig.2 Gram-scale anti-COX6A2 recombinant antibody production.
rAb Modalities
Creative Biolabs is committed to providing tools to help scientists make the next great discovery. As such, Creative Biolabs offers a variety of antibody modalities in multiple customizable formats to give researchers the flexibility they need for their anti-COX6A2 research.
Fig.3 Full-length anti-COX6A2 recombinant antibody production and modalities.
Probe the tissue-specific regulation of Complex IV with Creative Biolabs' high-quality anti-COX6A2 recombinant antibodies. Our portfolio of validated anti-COX6A2 products give you the isoform-specificity, purity, and activity needed to study this important subunit of Complex IV. Partner with Creative Biolabs for a reliable platform for your research. Contact our experts today.