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CRHBP

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Anti-CRHBP Recombinant Antibody Products

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For Research Use Only. Not For Clinical Use.


Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.
Protein class

Plasma proteins

Predicted location

Secreted

Single cell type specificity

Group enriched (Hepatic stellate cells, Granulosa cells)

Immune cell specificity

Not detected in immune cells

Cell line specificity

Cell line enhanced

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