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CRMP1
Loading...Anti-CRMP1 Products
- Rabbit Anti-CRMP1 Recombinant Antibody (clone JU73-30) (MRO-0393-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC, IP
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For Research Use Only. Not For Clinical Use.
CRMP1 (Collapsin Response Mediator Protein 1) is a Protein Coding gene. Among its related pathways are Semaphorin interactions and Developmental Biology. Gene Ontology (GO) annotations related to this gene include hydrolase activity and hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides. An important paralog of this gene is DPYSL3.
Predicted location
Intracellular
Single cell type specificity
Cell type enhanced (Horizontal cells, Bipolar cells, Muller glia cells, Inhibitory neurons, Excitatory neurons)
Immune cell specificity
Not detected in immune cells
Cell line specificity
Cell line enhanced (AF22, HAP1, NTERA-2, REH, RH-30, SCLC-21H, SH-SY5Y)
Interaction
Homotetramer, and heterotetramer with DPYSL2, DPYSL3, DPYSL4 or DPYSL5 (By similarity). Interacts with PLXNA1 (By similarity). Interacts with FLNA (via calponin-homology (CH) domain 1 and filamin repeat 24); the interaction alters FLNA ternary structure and thus promotes FLNA dissociation from F-actin (PubMed:25358863).
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