Anti-CTDSP1 Recombinant Antibody Products

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Anti-CTDSP1 Products

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For Research Use Only. Not For Clinical Use.


Creative Biolabs, is a research and development company focusing on advancing our understanding of molecular biology and gene regulation. We are proud to provide top-tier anti-CTDSP1 recombinant antibodies for your research. CTDSP1 is a phosphatase that dephosphorylates the C-terminal domain of RNA Polymerase II, a key transcriptional regulator. Our high-quality recombinant antibodies will allow you to dig deeper into the inner workings of gene expression, transcription termination, and the role of this phosphatase in development and disease.

CTDSP1: A Key Regulator of RNA Polymerase II

C-Terminal Domain Small Phosphatase 1 (CTDSP1), also known as CSRP1 and RPP30, is a nuclear phosphatase from the FCP1 family. Its main substrate is the C-terminal domain (CTD) of the largest subunit of RNA Polymerase II. The CTD of RNA Polymerase II consists of 52 repeats of a heptapeptide sequence in mammals. The phosphorylation state of the CTD acts as a dynamic code that regulates the entire transcription cycle. CTDSP1 specifically dephosphorylates serine-5 of these repeats. CTDSP1 has been suggested to be important for promoting transcription termination and recycling the polymerase for a new round of transcription, however its exact function is still not well understood.

Alternative Names

NIF3; SCP1; NLIIF; NLI-IF

Background

Protein class

Enzymes, Metabolic proteins, Plasma proteins

Predicted location

Intracellular

Single cell type specificity

Cell type enhanced (NK-cells)

Immune cell specificity

Low immune cell specificity

Cell line specificity

Low cell line specificity

Interaction

Monomer (By similarity). Interacts with GTF2F1. Interacts with REST.

Molecular function

Hydrolase, Protein phosphatase

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Anti-CTDSP1 rAb Products

Our recombinant anti-CTDSP1 antibodies are engineered to ensure maximum specificity and performance. They are thoroughly validated to specifically detect the CTDSP1 enzyme in nuclear extracts. These antibodies are optimized for applications such as Western Blot, IHC and Chromatin Immunoprecipitation (ChIP) to determine its association with gene bodies. Creative Biolabs' recombinant antibodies (rAbs) are the ultimate tool in your toolbox for reliable and precise results in molecular biology and gene regulation research.

Table 1. Featured anti-CTDSP1 recombinant antibody products at Creative Biolabs.

Cat. No. Product Name Target Species Host Species Applications
MOB-2019MZ Recombinant Mouse Anti-Human CTDSP1 Antibody (clone 2G5) Human Mouse IgG WB

Customer Reviews

Excellent
A**on
Recombinant Mouse Anti-Human CTDSP1 Antibody (clone 2G5)
The anti-CTDSP1 antibody from Creative Biolabs was exactly what we needed for our research project on transcription. It worked perfectly and we got a clean, specific band in the Western blot of nuclear fractions.
10/Jul/2024

rAb Production

Creative Biolabs' state of the art platforms and unique production platforms are constantly being updated to meet the needs of research fields such as gene regulation. Creative Biolabs' recombinant antibodies, including our anti-CTDSP1 rAb, are expressed in systems that have been optimized to ensure they are recognizing the native enzyme so that you get a highly specific and active antibody for your experiments.

Featured Anti-CTDSP1 Recombinant Antibody Production PlatformsFig.1 Milligram-scale. (Creative Biolabs Original)
Fig.1 Milligram-scale anti-CTDSP1 recombinant antibody production.

Fig.2 Gram-scale. (Creative Biolabs Original)Fig.2 Gram-scale anti-CTDSP1 recombinant antibody production.

rAb Modalities

Creative Biolabs is committed to enabling scientific discovery by providing flexible, customizable antibody solutions. Creative Biolabs' recombinant antibodies, including anti-CTDSP1 rAbs, are available in a variety of customizable modalities to meet your experimental needs. Order now from Creative Biolabs and help us to investigate the roles of this important transcriptional regulator across the globe.

Fig.3 CTDSP1 antibody production and modalities. (Creative Biolabs Original)Fig.3 Full-length anti-CTDSP1 recombinant antibody production and modalities.

Unlock the mysteries of CTDSP1 in transcription using the superior quality recombinant antibodies from Creative Biolabs. Our portfolio is characterized by high specificity and extensive validation to ensure you have the best tools for your research. Partner with us for quality that fuels discovery. Contact our experts today.

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