Anti-CYP2C9 Products

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For Research Use Only. Not For Clinical Use.

Creative Biolabs is your one-stop provider for drug metabolism and cardiology research, offering premium anti-CYP2C9 recombinant antibodies. CYP2C9 is the most abundant enzyme in the CYP2C subfamily and it is the predominant determinant of patient response to several drugs such as warfarin and NSAIDs. Our quality antibodies for CYP2C9 research enable you to study the in-depth pharmacogenomics and therapeutic dosing of this clinically significant enzyme.

CYP2C9: The Major Metabolizer of Warfarin

Cytochrome P450 2C9 (CYP2C9) is the most abundant monooxygenase enzyme in the CYP2C subfamily, and it is the single most important enzyme responsible for metabolizing a wide range of clinically used drugs. CYP2C9 metabolizes around 16% of all drugs, including the anticoagulant warfarin, numerous NSAIDs (such as ibuprofen), and oral hypoglycemics. This enzyme has high genetic polymorphism, with patients having low-activity variants requiring much lower dosages of drugs like warfarin in order to avoid life-threatening bleeding. CYP2C9 pharmacogenomics is, therefore, a critical component of personalized medicine.

Alternative Names

CPC9; CYP2C; CYP2C10; CYPIIC9; P450IIC9

Background

CYP2C9 (Cytochrome P450 Family 2 Subfamily C Member 9) is a Protein Coding gene. Diseases associated with CYP2C9 include Coumarin Resistance and Oral Antidiabetic Drugs Toxicity Or Dose Selection. Among its related pathways are Gefitinib Pathway, Pharmacokinetics and Statin Pathway - Generalized, Pharmacokinetics. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and heme binding. An important paralog of this gene is CYP2C19.

Anti-CYP2C9 rAb Products

Creative Biolabs' anti-CYP2C9 recombinant antibodies have been engineered for high specificity. They are carefully validated to specifically and reliably detect the CYP2C9 enzyme, without cross-reactivity with its highly homologous siblings (CYP2C8, 2C19). Optimized for a wide range of applications including Western Blot of liver microsomes and IHC, our rAbs have been validated to give you the reliability and specificity needed in pharmacological research.

Table 1. Featured anti-CYP2C9 recombinant antibody products at Creative Biolabs.

Customer Reviews

rAb Production

Creative Biolabs is equipped with the latest antibody production platforms to enable the production of antibodies for the specialized area of clinical pharmacology. Our anti-CYP2C9 recombinant antibodies are expressed in optimized systems that will ensure they specifically recognize the native enzyme in your application and provide a highly specific and active tool.

Featured Anti-CYP2C9 Recombinant Antibody Production Platforms
Fig.1 Milligram-scale anti-CYP2C9 recombinant antibody production.

Fig.2 Gram-scale anti-CYP2C9 recombinant antibody production.

rAb Modalities

Creative Biolabs is committed to powering scientific discovery by providing a wide range of flexible antibody solutions. Our anti-CYP2C9 recombinant antibodies are available in a variety of customizable modalities to help you with diverse applications.

Fig.3 Full-length anti-CYP2C9 recombinant antibody production and modalities.

Probe into the intricacies of drug metabolism using Creative Biolabs' high-quality anti-CYP2C9 recombinant antibodies. Our portfolio is characterized by the high level of validation and specificity you need to study this important enzyme in pharmacogenomics research. Rely on our expertise to build a robust foundation for your research. Speak to our specialists today.