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Cis pT231-MAPT

Anti-Cis pT231-MAPT Products
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ELISA, IHC, Neut
- Mouse Anti-Cis pT231-MAPT Recombinant Antibody; Fab Fragment (HPAB-0444-YJ-F(E)) (HPAB-0444-YJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, IHC, Neut, FuncS
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- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: ELISA, IHC, Neut, FuncS
- Mouse Anti-Cis pT231-MAPT Recombinant Antibody; Fab Fragment (HPAB-0445-YJ-F(E)) (HPAB-0445-YJ-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, IHC, Neut
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, IHC, Neut, FuncS
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, IHC, Neut
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For Research Use Only. Not For Clinical Use.
Background
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.