Enzymes, Plasma proteins
Intracellular
Group enriched (Early spermatids, Late spermatids)
Low immune cell specificity
Low cell line specificity
Part of the core SMN complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8 and STRAP/UNRIP (PubMed:10601333, PubMed:17178713). Part of the SMN-Sm complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, STRAP/UNRIP and the Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG (PubMed:18984161, PubMed:12095920). Interacts with SMN1; the interaction is direct (PubMed:17178713). Interacts with GEMIN4; the interaction is direct (PubMed:17178713). Interacts with GEMIN5 (PubMed:33963192). Interacts with SNUPN; the interaction is direct (PubMed:12095920). Interacts with PPP4R2 (PubMed:12668731). Interacts with FOXL2 (PubMed:16153597). Interacts with EBV EBNA2 and EBNA3C (PubMed:10383418). Interacts with NANOS1 and PUM2 (PubMed:21800163).
DNA-binding, Helicase, Hydrolase
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For Research Use Only. Not For Clinical Use.